21 Nisan 2012 Cumartesi

How Pregnancy Affects the Thyroid Gland

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A normal pregnancy causes substantial changes in the thyroid gland interfering with thyroid hormone production. Pregnancy places an increased pressure and demand on the thyroid gland.

In pregnancy, certain hormones and estrogen are produced at higher levels than normal. This will in turn cause an increase in the thyroid hormone levels in the blood. Estrogen on the other hand increases the production of thyroid-binding globulin - the protein responsible for transportation of thyroid hormone in the blood.

These hormone changes and variations do make it thyroid function tests harder to interpret if due to pregnancy hormones or if there is a true thyroid disorder.

As thyroid hormones are critical in baby's brain and nervous system development, pregnant women need more iodine. They need at least 250 mcg per day as there is not enough iodine in prenatal vitamins.

In persons without previous thyroid problems, pregnancy may or may not result in a full-blown thyroid disease. But in persons with previous thyroid problems, this extra demand of pregnancy on the thyroid gland may cause a more serious clinical disease and will need extra care by the physician.

Hyperthyroidism in Pregnancy

Hyperthyroidism diagnosis in pregnancy can be quite difficult as there are alterations in the hormones commonly used for diagnosis. The symptoms are just the same with a person who has hyperthyroidism but is not pregnant. There will be fatigue and hair falling out. In pregnant persons, normal pregnancy weight gain will be more difficult.

The most common result of hyperthyroidism in pregnancy is Grave's disease. It is an autoimmune disease that causes too much production of thyroid hormones.

Here are some of the consequences related to hyperthyroidism in pregnancy:

Hyperemesis gravidarum - severe nausea and vomitingMiscarriage or spontaneous abortionPreterm labor/Premature birthLow birth weight babiesStillbirthsPreeclampsiaCongestive heart failureThyroid storm

Mild cases do not require treatment. However, more severe cases might need treatment with propylthiouracil or methimazole.

Hypothyroidism in Pregnancy

The most common cause of hypothyroidism in pregnancy is Hashimoto's disease. Similar with Grave's disease, Hashimoto's thyroiditis alters the hormone production.

Hypothyroidism in pregnancy could be due to an existing undiagnosed thyroid disorder or hyperthyroidism treatment resulting in prior treatment of removal of the thyroid gland. Symptoms could be extreme fatigue, muscle cramps, constipation, and memory problems.

Here are some of the consequences related to hypothyroidism in pregnancy:

Congestive heart failurePreeclampsiaMiscarriageLow birth weightStillbirthsAnemia

Hypothyroidism treatment in pregnancy is usually through intake of a synthetic thyroxine. Thyroid medications are known to be safe for use during pregnancy.

Dr. Jonathan Berns, D.C. helps people everyday in the Tampa, Florida area overcome the very misunderstood and often mistreated conditions caused from dysfunctional thyroids. Visit Tampa Thyroid Program at Integrative Physical Medicine of Tampa to learn more about thyroid management.

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